Why Shingles Vaccination is Important?

Shingles is caused by reactivation of the varicella zoster virus in people who previously have had chicken pox.1,2

1 in 3 people will get shingles in their lifetime.3

Shingles may lead to long-term complications such as postherpetic neuralgia (PHN), herpes zoster ophthalmicus (HZO) or hearing issues.2
Shingles causes vesicular rash with a unilateral and dermatomal distribution is always accompanied by pain.1

SHINGRIX (zoster vaccine recombinant, adjuvanted) for shingles

SHINGRIX is the first licensed non-live antigen/ adjuvant system vaccine for shingles.4
SHINGRIX is an FDA-approved vaccine for prevention of shingles.4
SHINGRIX vaccine is proven to be more than 97% effective in preventing shingles in adults 50 years and older.5
SHINGRIX offers up to 10 years (89%) post vaccination efficacy against shingles.6

SHINGRIX vaccine given as a 2-dose series, with second shot administered 2 to 6 months after first shot.4​

For immunodeficient or immunosuppressed individuals, SHINGRIX vaccine are given in shorter vaccination schedule; first dose at month 0 and second dose within 1 to 2 months later.4

Who needs SHINGRIX?

  • CDC recommends SHINGRIX to prevent shingles and its complication in adults above 50 years.2
  • SHINGRIX has 97% proven efficacy in adults ≥50 years and 91% in adults ≥70 years.1,5

  • SHINGRIX for adults above 18 years who are at increased risk of shingles (immunocompromised individuals)4

CDC: Centre for Disease Control and Prevention; HZO: herpes zoster ophthalmicus; PHN: postherpetic neuralgia

Shingrix Safety Information4​
Contraindication: Hypersensitivity to the active substances or to any component of the vaccine. Very common adverse events include headache, gastrointestinal symptoms (including nausea, vomiting, diarrhea and/or abdominal pain), myalgia, injection site reactions (such as pain, redness, swelling), fatigue, chills, fever. ​

References:

  1. Lal H, et al. N Engl J Med. 2015 May 28;372(22):2087-96
  2. CDC. Shingles [Internet]. Centers for Disease Control and Prevention. 2019. Available from: https://www.cdc.gov/shingles/about/index.html. Accessed September 2024.
  3. Bollaerts K, et al. Epidemiol Infect. 2017; 145(13):2666-2677
  4. Shingrix Prescribing Information
  5. Cunningham AL, et al. N Engl J Med. 2016;375(11):1019-32.
  6. Strezova A, et al. Open Forum Infect Dis. 2022;23:9(10)
  7. CDC. Shingles [Internet]. Centres for Disease Control and Prevention. 2019. Available from: https://www.cdc.gov/shingles/about/index.html. Accessed September 2024

For Malaysia Healthcare Professionals Only

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Shingrix Prescribing Information

Before prescribing, please refer to the full prescribing information, which is available via scanning this QR code. For any issues accessing the prescribing information via QR code, please contact GSK Malaysia at medinfo.my@gsk.com.​

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